Research progress of the antidepressants targeting the glutamate receptors / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 1197-1200, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-456625
ABSTRACT
Depression is a worldwide neuropsychiatric disorder. Currently most preclinical and clinical studies of depression focus on monoaminergic system. However, there is growing evidence which suggests that glutamatergic system plays a critical role in the pathophysiology of depression. This review focuses on the de-velopment of new antidepressants that target glutamatergic sys-tem, summarizes the current mechanisms of antidepressants, and also highlights new insights to the pathophysiology of depression.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2014
Type:
Article
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