Two Cases of Stevens-Johnson Syndrome

ABSTRACT

The authors presented two cases of Stevens-Johnson syndrome in each 27-and 30-year old male, aad the review of the literature was given. In both patients, there were acute onset of fever followed by erythematous and bullous lesions on the skin and involvement of the mucous membranes, including the eyes. Ocular manifestations were those of pseudomembranous form such as severe conjunctivitis with conjunctival scarring, symblepharon, and superficial punctate corneal opacity. Although there left mild superficial punctate opacity of the cornea. visual acuity was almost unchanged in case I. However, in case II, the patient continued to complain of disabling photophobia and severe irritation possibly due to punctate corneal infiltrations and conjunctival dryness. We considered that decreased conjunctival and lacrimal secretion caused by conjunctival scarring had contributed to keratitis. In this patient, the vision was also decreased in some degree.