Stability of Jinyin Qingre Oral Liquid / 医药导报
Herald of Medicine
;
(12): 1502-1505, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-458210
ABSTRACT
Objective To investigate the stability of jinyin qingre oral liquid. Methods According to the stability test guidelines for pharmaceutical preparations,the appearance,pH and relative density of jinyin qingre oral liquid were detected, the contents of geniposide,chlorogenic acid and salvia acid B were determined by HPLC. The chromatographic conditions were as followsAtlantisT3 column(150 mm×4. 6 mm,3 μm),mobile phase A0. 05% phosphoric acid,mobile phase Bacetonitrle, gradient elution at the flow rate of 0. 8 mL · min-1 ,and column temperature at 35 ℃. The detection wavelength was set at 254 nm. Results The appearance,pH,and relative density of jinyin qingre oral liquid did not change significantly with the acceleration test,but the contents of geniposide,chlorogenic acid and salvia acid B decreased time dependently. Conclusion Light and high temperature could decrease the stability of the jinyin qingre oral liquid.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Herald of Medicine
Year:
2014
Type:
Article
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