Regulation and significance of acidification of plasma membrane and intracellular membranes / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1223-1225, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-458372
ABSTRACT
Acidic environment of organelles of eukaryotic cells plays an important role in endocytosis, the secretion of lysoso-mal enzymes and other physiological activities.V-ATPase (vacuolar ATPases) and CLC (chloride channel) family are widely distribu-ted and present in virtually all eukaryotic cells in intracellular membranes and in the plasma membrane.They are responsible for the a-cidification of the vesicular interior.In this paper, the distribution, structure, mechanism of action and physiological and pathological significance of V-ATPase and CLC protein are discussed.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2014
Type:
Article
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