Relationship between plasma rennin levels in ischemic stroke patients and aspirin-induced gastrointestinal bleeding / 重庆医学

ABSTRACT

Objective To investigate the relationship between plasma rennin levels in ischemic stroke patients and aspirin-in-duced gastrointestinal bleeding .Methods 50 ischemic stroke cases in neurology department of the Second Affiliated Hospital of Chongqing Medical University from June 2012 to December 2012 were collected and divided into 2 groups depended plasma rennin levelslow rennin group and high rennin group .Low rennin group contained 21 cases and high rennin group containd 29 cases .Ap-pearance of haematemesis ,melena and fecal occult blood were considered as positive identification ,peptic ulcer bleeding in endoscope or death as the endpoint event in 1 year follow-up .Comparison of the incidence of gastrointestinal bleeding between 2 groups was made .Results The average age of patients in low rennin group was higher than that in high rennin group(P0 .05) .Conclusion Different plasma rennin levels in ischemic stroke pa-tients may be unrelated to aspirin-induced gastrointestinal bleeding .