Research progress of virus-like particles and its application in the prevention and control of infectious diseases / 中华检验医学杂志

ABSTRACT

Virus-like particles ( VLPs ) are particles formed by one or several structural proteins from viruses with similar outside structure and antigenicity of the native viruses containing no virus genome.VLPs antigen can be produced in yeasts, mammalian cells, plant cells, insect cells and bacteria.VLPs vaccine can induce immune response effectively.Other adjuvant or polypeptide can be integrated into VLPs to construct chimeric vaccines.This review focuses on research progress of virus-like particles and its application in the prevention and control of infectious diseases.