Study on Quality Standard for Aitongxiao Granules / 中国药师
China Pharmacist
;
(12): 1859-1861, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-460038
ABSTRACT
Objective:
To establish the quality standard for Aitongxiao granules.Methods:
TLC was used to identify Herba Hedy-otis Diffusa, Herba Scutell Barbatae, Radix Astragali and Radix Paeoniae Rubra in Aitongxiao granules, and the content of scutellarin was determined by HPLC. The stationary phase was a Kromasial C18 column (250 mm × 4. 6 mm,5μm), the mobile phase was metha-nol-3% acetic acid (33∶67), the flow rate was 1. 0 ml·min-1, the detection wavelength was at 335 nm, and the temperature was 25℃.Results:
The characteristic TLC spots of the granule samples were the same as those of the standard samples without any inter-ference from the negative control. Scutellarin had a good linear relationship within the range of 2.18-10.90μg·ml-1(r=0.999 9), and the average recovery was 96. 65% with RSD of 1. 45﹪(n=6).Conclusion:
The method is simple, accurate, reliable and repro-ducible, which could be used in the quality control of Aitongxiao granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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