Therapeutic effect of telmisartan combined nifedipine in patients with obese and hypertension / 心血管康复医学杂志

ABSTRACT

Objective:To explore the therapeutic effect of telmisartan combined nifedipine in patients with obese and hypertension and its influence on patients′blood lipid level.Methods:A total of 180 patients with obese and hyper-tension,who hospitalized in our hospital from Jan 2011 to Dec 2012,were enrolled as subjects.According to random number table method,they were equally divided into nifedipine group and nifedipine combined telmisartan group (combined medication group).Therapeutic effects,changes of levels of blood lipids etc.were observed in two groups.Results:After six-week treatment,compared with nifedipine group,total effective rate of combined medi-cation group significantly rose (75.56%vs.93.33%,P <0.05);the levels of total cholesterol [TC,(5.20±0.59) mmol/L vs.(4.75±0.73)mmol/L],triglyceride [TG,(1.87±0.49)mmol/L vs.(1.67±0.48)mmol/L]and blood pressure [(138±9)/ (90±6)mmHg vs.(125±9)/ (81 ±5)mmHg]significantly reduced in combined medication group,P <0.05 all.Conclusion:Telmisartan combined nifedipine possess significant therapeutic effect on obese and hypertension,it also can lower blood lipid levels.