Relationship between coronary heart disease and glucose metabolism disorder / 心血管康复医学杂志

ABSTRACT

Objective:To explore the relationship between coronary heart disease (CHD)and glucose metabolism dis-order.Methods:A total of 512 CHD patients received glucose tolerance test and coronary angiography,the percent-age of patients with impaired glucose tolerance (IGT)was counted,and degree of coronary disease was compared a-mong patients with different glucose tolerance.Results:Besides the 166 patients already diagnosed as diabetes melli-tus (DM),among the resting 346 patients undergoing oral glucose tolerance test (OGTT),there were 74 cases (21.39%)of new-onset DM and 152 cases (43.93%)of impaired glucose regulation (IGR).A total of 240 DM pa-tients occupied as high as 46.88% among the total 512 subjects.Compared with OGTT results,omission diagnose rate of DM was 43.2% and it′s 73.7% for IGR by single measuring fasting plasma glucose (FPG);compared with normal glucose tolerance (NGT)and IGT group,there were more of ≥ 3 vessel coronary disease (20.83% vs. 30.92% vs.58.75%)in DM group,P <0.05~ <0.01.Conclusion:Most CHD patients complicate with glucose metabolism disorder.Percentage of patients with≥ 3 vessel coronary disease is significant rise in DM group than those of NGT and IGT group.OGTT can significantly raise detection rate of glucose metabolism disorder.