The Early Diagnostic Value of Thyroid Hormone Level in Patients With Left Ventricular Diastolic Dysfunction / 中国循环杂志

ABSTRACT

Objective: To explore the early diaghostic value of thyroid hormone level in patients with left ventricular diastolic dysfunction. Methods: Our work included 4 groups①Normal control group, n=40,②Impaired left ventricular diastolic function group, n=40,③Failure of left ventricular diastolic function group, n=41 and④Impaired left ventricular systolic function group, n=40. The cardiac function was assessed by color Doppler lfow imaging and tissue Doppler imaging for the early diastolic mitral lfow velocity (E), the peak early diastolic mitral annular velocity (Em) and the ratio of E/Em. The blood levels of NT-proBNP and FT3, FT4, TSH, rT3 were examined in clinical laboratory. Results: Blood levels of FT3 and rT3 were different in pair wise comparison among 4 groups, P0.05. The ratio of E/Em was negatively related to FT3 (r=-0.724, P Conclusion: The changes of thyroid hormone level may exist in patients with impaired diastolic function and it may vary with the severity of the cardiac dysfunction. Blood levels of NT-proBNP with thyroid hormone might be used as a reference index for early diagnosis of diastolic dysfunction.