Research progress in the relationship between VEGF and leukemia / 白血病·淋巴瘤

ABSTRACT

The levels of multiple vascular endothelial growth factor (VEGF) in patients with hematological malignancies are up-regulated,which associate with disease outcome.VEGF is a major cytokine involved in angiogenesis,and has been related to a variety of functions of endothelial cells.This paper reviews the role of VEGF in leukemia,and discusses the latest development of placenta growth factor in chronic myeloid leukemia.