Associations between polymorphisms of Vitamin D receptor gene and type 1 diabetes susceptibility:A meta-analysis / 中国糖尿病杂志
Chinese Journal of Diabetes
;
(12): 110-114, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-461045
ABSTRACT
Objective To explore the associations between polymorphisms of Vitamin D receptor gene and type 1 diabetes susceptibility. Methods Literatures were retrieved from PubMed ,Web of Science and WanFang databases ,etc.Pooled odds ratios(ORs) with 95% confidence intervals (CIs) were calculated using a random effect model. Results A total of 28 literatures were included. The result of analysis showed that BsmI and ApaI polymorphism were the susceptibility gene for T 1DM in Asian populations [B vs b;OR(95% CI)=1.53(1.06~2.20) ,P=0.024 ;AA vs aaOR(95% CI)=1.60(1.06~2.40) ,P= 0.023]. Conclusion The BsmI and ApaI polymorphism may be susceptibility gene in Asians populations with T1DM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Systematic reviews
Language:
Chinese
Journal:
Chinese Journal of Diabetes
Year:
2015
Type:
Article
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