Effect of dihydroartemisinin on cell proliferation and radiotherapy sensitization of lung cancer cell H1299 / 中国免疫学杂志
Chinese Journal of Immunology
;
(12): 185-188, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-461982
ABSTRACT
Objective:
To investigate the inhibitory effect of dihydroartemisinin on non-small cell lung cancer H1299 cells.Methods:
Through the CCK-8 method for determining the IC 10 of dihydroartemisinin ,choose low dose IC 10 as the experimental concentration,CCK-8 to observe artemisinin in low doses of H1299 cell proliferation, cycle and the influence of radiation sensitivity.Results:
IC10 of dihydroartemisinin was 14.87 μmol/L,dihydroartemisinin could inhibit proliferation of H 1299 cells,slow down the cell cycle , and increased the radiation sensitivity.Conclusion:
Dihydroartemisinin can inhibit cell proliferation , cell cycle arrest in S phase ,increase the radiation sensitivity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2015
Type:
Article
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