Anti-inflammatory and Analgesic Activity of Rupixiao Granules / 中国药师
China Pharmacist
; (12): 149-151, 2015.
Article
in Zh
| WPRIM
| ID: wpr-462501
Responsible library:
WPRO
ABSTRACT
Objective:To investigate the anti-inflammatory and analgesic effects of Rupixiao granules. Methods:Activity of Rupixi-ao granules against xylene-induced ear edema in mice was measured to evaluate the anti-inflammatory effect, while the analgesic effect was evaluated by acetic acid induced writhing test and hot plate test in mice. Results:Compared with the control group, Rupixiao gran-ules groups (1. 0, 2. 0 and 4. 0 g·kg·d-1) could significantly inhibit ear swelling in mice(P<0. 05 or 0. 001), and reduce the acetic acid induced writhing times(P<0. 01 or 0. 001). Rupixiao granules at medium and high dose could significantly increase the pain thresh-old of mice in the hot plate test. Conclusion:Rupixiao granules exhibit significant anti-inflammatory and analgesic activities.
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacist
Year:
2015
Type:
Article