Curative Effect of Lacidophilin Vaginal Capsules Combined with Loop Electrosurgical Excisional Procedure in the Treatment of Cervical Erosion with Chronic Cervicitis / 中国药师

ABSTRACT

Objective:To discuss the curative effect of lacidophilin vaginal capsules combined with loop electrosurgical excisional procedure ( LEEP) in the treatment of cervical erosion with chronic cervicitis. Methods:Totally 72 cases of patients with cervical ero-sion with chronic cervicitis were selected and divided into the observation group and the control group at random. The patients in the two groups were given routine LEEP with the application of antibiotics to prevent infection for 1 week. The patients in the observation group were additionally given lacidophilin vaginal capsules, placed in the vagina after the operation, one capsule per time at every night for 14 days. The vaginal fluid time and vaginal bleeding time in the two groups were observed. The clinical curative effect and adverse drug reactions ( ADRs) after 8 weeks of the operation were studied and evaluated again. Results: The vaginal bleeding amount and bleeding time in the observation group after the operation was less or shorter than that in the control group (P<0. 05). According to the further consultation after 8 weeks of the operation, the total clinical efficiency in the observation group was 94. 44%, which was ob-viously higher than that in the control group(75. 00%,P<0. 05). There was no obvious ADR appeared in the two groups during the treatment. Conclusion:Lacidophilin vaginal capsules combined with LEEP has reliable curative effect on cervical erosion with chronic cervicitis, which can obviously shorten the wound healing time and decrease the vaginal bleeding amount and time with high security.