Study on the Nutrition Status in Patients with COPD / 医学研究杂志

ABSTRACT

Objective To investigate the parameters of nutrition status in the patients with COPD and study the difference nutrition status among COPD GOLD classification including A, B,C and D.Methods According to the global initiative for chronic obstructive lung disease ( GOLD) criteria, we classified the COPD outpatients into A, B, C, D group, with 10 cases in each group, 20 cases healthy people as control group as well as 20 patients with chronic bronchitis.Body mass index ( BMI) , triceps skin-fold thickness( TSF) ,ser-um albumin ( ALB ) were measured in each person.Results BMI was significantly lower in COPD group than health control group (21.3 ±4.0kg/m2 vs 24.7 ±3.7kg/m2, P<0.01) ; TSF was significantly reduced in COPD group than the control group (10.3 ± 4.4mm vs 13.0 ±4.4mm, P<0.05);ALB in COPD group was significant decreased than the control group (34.4 ±5.3g/L vs 39.5 ± 6.7g/L, P<0.01).Moreover, there were significantly differences in the nutrition status among COPD groups.BMI in the group of(C+D) was significantly lower compared with the group of (A+B) (19.9 ±4.3kg/m2 vs 22.1 ±3.5kg/m2, P<0.05).TSF was significant-ly decreased in the group of (C+D) than the group of (A+B)(7.7 ±2.4mm vs 12.9 ±4.4mm, P<0.01).Compared with the group of (A+B), ALB was also significantly reduced in the group of (C+D)(32.3 ±4.5g/L vs 36.5 ±5.4g/L, P<0.01).Conclusion The parameters of BMI, TSF, ALB are significantly reduced in the patients with COPD.Severe COPD easily develops malnutrition.Ac-cording to COPD GOLD classification, the nutrition status is worse in the group of ( C+D) than in the group of ( A+B) .It is worthy to pay attention to the nutrition status of COPD patients, and give appreciate therapy for patients with COPD.