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Surveillance of minimal residual disease in acute B-lineage lymphoblastic leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma ; (12): 248-250, 2013.
Article in Zh | WPRIM | ID: wpr-462723
Responsible library: WPRO
ABSTRACT
Minimal residual disease (MRD) is the cause of relapse in leukemia,and its dynamic monitoring has been a hotspot yet proven to be difficult.MRD in acute B-lineage lymphoblastic leukemia has its own characteristics,normal bone marrow produces a large number of B precursor cells,easily mistaken for leukemia cells,and there were no specific gene alterations that can be conveniently detected.This paper summarizes the antibody combinations in flow cytometry,timing for surveillance and polymerase chain reaction for gene detection,and provide a reference for B lymphocytic leukemia MRD monitoring.
Key words
Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Journal of Leukemia & Lymphoma Year: 2013 Type: Article
Full text: 1 Index: WPRIM Type of study: Screening_studies Language: Zh Journal: Journal of Leukemia & Lymphoma Year: 2013 Type: Article