Surveillance of minimal residual disease in acute B-lineage lymphoblastic leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 248-250, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-462723
ABSTRACT
Minimal residual disease (MRD) is the cause of relapse in leukemia,and its dynamic monitoring has been a hotspot yet proven to be difficult.MRD in acute B-lineage lymphoblastic leukemia has its own characteristics,normal bone marrow produces a large number of B precursor cells,easily mistaken for leukemia cells,and there were no specific gene alterations that can be conveniently detected.This paper summarizes the antibody combinations in flow cytometry,timing for surveillance and polymerase chain reaction for gene detection,and provide a reference for B lymphocytic leukemia MRD monitoring.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2013
Type:
Article
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