Advances research in chromatin DNaseⅠhypersensitive sites and its transcriptional regulation function / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 666-669, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-463473
ABSTRACT
DNaseⅠhypersensitive sites (DHSs) are regions of extreme chromatin which is highly sensitive to DNaseⅠ.Ge-nome-wide mapping DHSs is a powerful method for identifying many different types of regulatory elements within nuclear chromatin .It can help systematically resolve gene and genomic information , and the dynamic molecular mechanism of transcriptional regulation .This paper reviews the distribution of DHSs , the technology of DNase-seq and the research progress in transcriptional regulation functions of DHSs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2015
Type:
Article
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