The application of the external treatment of Glauber′s salt on cytokines of acute pancreatitis patients / 中国基层医药

ABSTRACT

Objective To discuss the application of glauber's salt external impact on cytokines in patients with celiac inflammation and clinical application value.Methods Clinical data of 180 patients with acute pancreatitis were retrospectively analyzed.According to the different treatment,they were divided into the observation group and control group,the control group were treated by routine western medicine,the observation group were treated with mirabilite topical therapy,records of two groups of patients with clinical therapeutic effect.Results The total effective rate of the observation group was 92.22%,which of the control group was 82.22%.The differences between the two groups was statistically significant (χ2 =4.037,P <0.05).The cytokines concentrations of the observation group after treatment were as followsTNF alpha (40.02 ±5.19)ng/L,IL -6 (32.93 ±7.65)ng/L,IL -8 (23.41 ±3.86)ng/L, NF -κB (85.36 ±19.65)U /L;those in the control group after treatmentTNF alpha (63.38 ±8.97)ng/L,IL -6 (56.73 ±11.16)ng/L,IL -8 (40.85 ±7.43)ng/L,NF -κB (231.32 ±41.28)U /L,statistical analysis showed that contrast differences among groups with statistical significance (t =21.384,16.687,19.760,16.687,all P <0.05).The observation group (3.18 ±1.33)d abdominal distension relief time,gastrointestinal function recovery time (5.64 ±1.86)d,length of hospital stay (15.13 ±3.76)d;The control group (5.64 ±2.31)d abdominal distension relief time,gastrointestinal function recovery time (8.96 ±3.45)d,length of hospital stay (24.59 ±5.87)d;Statisti-cal analysis showed that contrast differences among groups with statistical significance(t =8.755,8.035,12.874,all P <0.05).Conclusion Using glauber's salt topical application in patients with celiac inflammation can effectively reduce inflammation in the body,improve the treatment effect,to speed up the patients with gastrointestinal functional recovery,which is worth popularization and application in clinic.