Optimization of the Formula of Konjac Glucomannan-Paeonol Matrix Tablets / 医药导报
Herald of Medicine
;
(12): 502-505, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-464638
ABSTRACT
Objective To optimize the formula of konjac glucomannan-paeonol matrix tablets. Methods The formula of paeonol matrix tablets was optimized by the orthogonal design with the accumulative release rate in vitro as index, with the viscosity of konjac glucomannan ( KGM) , the amount of KGM and lactose as influence factors. Results The optimized formula was as followsthe viscosity of konjac glucomannan was 20 000 mPa·s, KGM 30%, lactose 20% and the release in vitro fit into the Higuchi equation. Conclusion The formula of the paeonol matrix tablets is reasonable and the tablets have well release effect in vitro.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Herald of Medicine
Year:
2015
Type:
Article
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