Application of circulating tumor cells detection in non-small cell lung cancer / 国际肿瘤学杂志

ABSTRACT

Circulating tumor cells(CTCs)are essential for establishing metastasis and recurrence in non-small cell lung cancer(NSCLC). With the development of detection technique,results from recent studies suggest that CTC level could be a supplement for TNM staging system and a prediction marker of prognosis and therapeutic efficacy,and even could be applied for risk assessment of early NSCLC. Furthermore,as a non-invasiveliquid biopsy,detection of CTC can reflect the molecular biology and genetics characteristics of the primary tumor,and subsequently assist in selecting an optimal individualized treatment.