Proto-oncogene Bmi-1 and non-small cell lung cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 295-297, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-464989
ABSTRACT
B-cell specific moloney leukemia virus insertion site 1(Bmi-1)gene is a core member of the polycomb group genes,considered to be a proto-oncogene;Bmi-1 plays an important role in cell self-renewal, proliferation and apoptosis. Several studies have shown that Bmi-1 is highly expressed in non-small cell lung cancer;furthermore,the expression level of Bmi-1 is closely related to the occurrence,development,incursion and prognosis of non-small cell lung cancer. Bmi-1 is expected to become a novel tumor molecular marker,and provides a new direction for the treatment of non-small cell lung cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2015
Type:
Article
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