COX-2 and its inhibitors in lung cancer drug resistance / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 203-205, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-465048
ABSTRACT
COX-2 is the inducible form of cyclooxygenase,which is overexpressed in non-small cell lung cancer,especially in the adenocarcinoma,and is involved in the production of lung cancer drug resistance, reducing the sensitivities of tumor cells to chemotherapy drugs. COX-2 inhibitors have the effects of antitumor and prevention of tumor formation. Therefore,in order to reverse the drug resistance of tumor cells,improve the sur-vival rate and the prognosis of patients with tumor,the application of COX-2 inhibitors as adjuvant chemotherapy and combined with chemotherapy drugs has become a new direction in the treatment of lung cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS