Clinicopathologic Features of Colorectal Cancer Combined with Synchronous and Metachronous Gastric Cancer / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 27-32, 2013.
Article
in Korean
| WPRIM
| ID: wpr-46506
ABSTRACT
BACKGROUND/AIMS:
The purpose of this study was to investigate the clinicopathologic features of double primary cancers of the stomach and colorectum, compared to colorectal cancer alone.METHODS:
A retrospective analysis was made of 5,288 patients who underwent colorectal cancer surgery between January 2000 and December 2009 at Severance Hospital of Yonsei University. The clinicopathologic features were analyzed between 63 patients of double primary cancers and case-matched 126 patients of colorectal cancer alone. We classified double primary cancers into subgroups as premetachronous, synchronous and postmetachronous gastric cancer to identify differences between the three subgroups also.RESULTS:
Double primary cancers group showed 4.3 year-older age, lower BMI, and higher percentage of peritoneal metastasis, compared to colorectal cancer alone group. Overall and colorectal cancer specific survival did not have any significant difference between two groups. In histologic type of gastric cancer, a high percentage of undifferentiated adenocarcinoma (55.6%) and signet ring cell carcinoma (30.2%) were noted.CONCLUSIONS:
Double primary cancers of the stomach and colorectum had older-age onset, lower BMI and higher metastasis to peritoneum than colorectal cancer alone. Combined gastric cancer consisted of high percentage of undifferentiated and signet ring cell carcinomas.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peritoneal Neoplasms
/
Polyps
/
Stomach Neoplasms
/
Colorectal Neoplasms
/
Adenocarcinoma
/
Body Mass Index
/
Odds Ratio
/
Retrospective Studies
/
Age Factors
/
Carcinoma, Signet Ring Cell
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2013
Type:
Article
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