Relationship Between Lipid Control Level and In-stent Restenosis in Patients After Percutaneous Coronary Intervention / 中国循环杂志
Chinese Circulation Journal
;
(12): 644-646, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-465105
ABSTRACT
Objective:
To investigate the relationship between lipid control level and in-stent restenosis (ISR) in patients after percutaneous coronary intervention (PCI).Methods:
A total of 211 coronary artery disease (CAD) patients who received primary PCI in our hospital from 2012-01 to 2012-12 were studied. All the patients took oral dual anti-platelet therapy and statins routinely, and they received coronary angiography (CAG) re-examination at (3-12) months after PCI. According to CAG ifndings, the patients were divided into 2 groups ISR group,n=25 and Non-ISR group,n=186. Blood levels of TC, TG, HDL-C, LDL-C were detected and compared before primary PCI and after CAG re-examination between 2 groups.Results:
The baseline information such as age, gender, hypertension, family history of CAD, pre-operative diagnosis of coronary syndrome, smoking and drinking conditions were similar between 2 group,P>0.05; the pre-operative TC, TG, HDL-C, LDL-C were similar between 2 group,P>0.05. CAD patients combining with diabetes mellitus (DM) in ISR group (36.0%) was higher than that in Non-ISR group (17.7%),P=0. 03. Multivariate logistic regression analysis showed that at post PCI, no TC reduction (OR=1.07, 95% CI 0.38-2.62,P=0.04), LDL-C ≥ 1.8 mmol/L or the reduction less than 50% (OR=11.33, 95% CI 3.62-35.52,P<0.01), combining with DM (OR=3.00,95% CI 1.04-8.67,P=0.04) were positively related to ISR.Conclusion:
Without TC reduction and nonstandard LDL-C level were the risk factors of ISR occurrence in CAD patients after PCI, DM complication may signiifcantly increase the risk of ISR.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2015
Type:
Article
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