Double-Blind Study of Intrarectal Administration of Anesthetic Agent for Pain Control during Transrectal Prostatic Biopsy / 대한남성과학회지
Korean Journal of Andrology
;
: 153-156, 2002.
Article
in Korean
| WPRIM
| ID: wpr-46577
ABSTRACT
PURPOSE:
We evaluated the safety and efficacy of intrarectal administration of anesthetic agent for transrectal prostate biopsy. MATERIALS ANDMETHODS:
For a double-blind prospective trial, 100 men undergoing transrectal prostate biopsy were randomized into three groups using an established list. In the control group (n=36), 40mL of normal saline was administered transrectally 10 min before the procedure. The lidocaine group (n=31) and the benzocaine group (n=33) were give 40 mL of 1% lidocaine and 0.3% benzocaine, respectively. Patients were asked to score the severity of the pain expected before and after the biopsy procedure using a self-administered verbal rating scale. Pain was assessed using a 10-point linear visual analog scale.RESULTS:
The median pain score expected before the transrectal prostate biopsy was 6.7+/-0.3, 7.1+/-0.2, and 6.7+/-0.3 in the control, lidocaine, and benzocaine group, respectively. The median pain score during the biopsy was 6.1+/-0.3, 5.8+/-0.3 (P<0.05), and 5.9+/-0.4 in the control, lidocaine, and benzocaine group, respectively. Ninety seven percent of the control group, 100% of the lidocaine group, and 91% of the benzocaine group complained of severe and bothersome pain, with a score of 5 or greater during the biopsy. No adverse events were noted.CONCLUSIONS:
Intrarectal administration of anesthetic agent is a simple, safe, and efficacious method of providing satisfactory anesthesia in patients undergoing transrectal prostate biopsy. We recommend 1% lidocaine solution in the patients to perform transrectal prostatic biopsy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostate
/
Benzocaine
/
Biopsy
/
Double-Blind Method
/
Prospective Studies
/
Visual Analog Scale
/
Anesthesia
/
Anesthetics
/
Lidocaine
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Andrology
Year:
2002
Type:
Article
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