Therapeutic effect of citicoline in vascular cognitive impairment / 国际脑血管病杂志

ABSTRACT

Vascular cognitive impairment refers to all cognitive impairment syndromes associated with vascular diseases,including severe cognitive impairment from mild cognitive impairment to vascular dementia.Citicoline is a necessary intermediate of the phosphatidylcholine biosynthesis,an important component of the neuronal membranes.Experimental studies have shown that citicoline has neuroprotective and neurorepair effects in cerebral ischemia.Clinical studies have shown that citicoline may improve cognitive function in patients with vascular cognitive impairment.