A Case Report of a 37-Year-Old Alzheimer's Disease Patient with Prominent Striatum Amyloid Retention
Psychiatry Investigation
;
: 521-524, 2017.
Article
in English
| WPRIM
| ID: wpr-46657
ABSTRACT
With recent advancement in amyloid imaging, diagnostic application of this new modality has become a great interest among researchers. New ligands, such as 18F- florbetaben, florbetapir and flutemetamol, have been discovered to overcome limitations of preexisting ligand Pittsburgh compound B. We report here a case of a 37-year-old male patient whose initial complaints comprised of gradual cognitive decline, apraxia, disorientation and sleep disturbances. 18F-Florbetaben amyloid imaging of the patient showed diffuse amyloid retention with prominent striatal uptake. This finding supports the clinical utility of amyloid imaging in diagnostic process of early-onset AD. Moreover, striatal dominant uptake pattern demonstrated in this patient include some meaningful clinical implications that warrant special attention among clinicians.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Apraxias
/
Diagnostic Imaging
/
Alzheimer Disease
/
Amyloid
/
Ligands
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Psychiatry Investigation
Year:
2017
Type:
Article
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