Development of ABCC4 on various tumors and chemotherapy drugs / 国际肿瘤学杂志
Journal of International Oncology
; (12): 367-370, 2015.
Article
in Zh
| WPRIM
| ID: wpr-467414
Responsible library:
WPRO
ABSTRACT
ATP binding cassette C4(ABCC4,MRP4)plays an important role in transshipment physio-logic,endogenous or exogenous substances. The over expression of ABCC4 gene has been found in many kinds of solid tumors and hematological malignancies. The target gene also influences metastasis and recurrence process. ABCC4 can reduce the intracellular concentration and the sensitivity of various chemotherapy drugs, which is bad for prognosis.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of International Oncology
Year:
2015
Type:
Article