Comparative Study of Rivaroxaban and Warfarin for Treating the Patients With Left Ventricular Thrombus / 中国循环杂志
Chinese Circulation Journal
;
(12): 559-561, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-467835
ABSTRACT
Objective:
To compare the safety and efifcacy of rivaroxaban and warfarin for treating the patients with left ventricular thrombus.Methods:
A total of 31 patients with left ventricular thrombus were studied, the patients were randomly divided into 2 groupsWarfarin group, n=16, the patients initially received oral warfarin and low molecular weight heparin at (2.5-3) mg/day, when the INR value reached 2.0-3.0, heparin was stopped and warfarin was continued, the INR value was monitored every 3 days for 3 times, when INR value was stably kept at 2.0-3.0, it was then monitored for every 2 weeks. Rivaroxaban group,n=15, the patients received oral rivaroxaban at 10 mg twice a day. All patients were followed-up for 3 months, the thrombus remission time, new onset of thrombosis, embolism and bleeding events during treatment period were compared between 2 groups.Results:
The patients’ age, gender, complication, size of thrombus and medication were similar between 2 groups. Compared with Warfarin group, Rivaroxaban group had the shorter thrombus remission time, (60.00±5.50)d vs (71.00±8.50) d,P0.05.Conclusion:
Rivaroxaban had better effect than warfarin for treating the patients with left ventricular thrombus without increasing the risk of bleeding.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2015
Type:
Article
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