The levels of TGF-β1 in hypertensive renal function impairment patients and its clinical value analysis / 中国医学装备
China Medical Equipment
;
(12): 112-115, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-468032
ABSTRACT
Objective:
To detect the levels of TGF-β1 in hypertensive renal function impairment patients and its clinical value.Methods:
Primary hypertension patients with no target organs damage were enrolled in control group, primary hypertension patients with renal function stageⅠand stageⅡwere enrolled in renal function stageⅠgroup and stageⅡgroup. Serum TGF-β1 levels and renal function indices of three groups were compared.Results:
There were no significant difference of serum creatinine and blood urea nitrogen of three groups(F=23.523, P<0.05);endogenous creatinine clearance rate of renal functionⅠandⅡgroups were lower than that of control group, TGF-β1 levels of renal functionⅠandⅡ groups were higher than of control group; TGF-β1 levels were negatively correlated with creatinine clearance rate.Conclusion:
TGF-β1 level is an ideal index to reflect renal function for its level significantly changes in renal damage stageⅠ,Ⅱand has good correlation with Cin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Medical Equipment
Year:
2015
Type:
Article
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