Research of serum thyroid hormone levels in elderly congestive heart failure patients with depression / 中国医师进修杂志

ABSTRACT

Objective To explore the change of serum thyroid hormone levels in elderly congestive heart failure patients with depression.Methods A total of 122 elderly congestive heart failure patients were divided into two groupscombined group (combined with depression,53 cases) and control group (without depression,69 cases).The serum thyroid hormone levels were determined and the Hamilton Depression Inventory assessment was evaluated.The serum thyroid hormone levels and the incidence of low T3 syndrome were compared between two groups.Results The serum free three iodine thyronine,free thyroxine,thyroid stimulating hormone concentration in combined group was lower than that in control group [(3.12 ± 0.91) pmol/L vs.(3.94 ± 1.09) pmol/L,(12.93 ± 3.89) pmol/L vs.(15.71 ± 4.01) pmol/L,(2.25 ± 0.63) mU/L vs.(2.86 ± 0.83) mU/L],and there was significant difference (P ＜ 0.01 or ＜ 0.05).The incidence of low T3 symdrome in combined group (43.40％,23/53) was higher than that in control group (13.04％,9/69),and there was significant difference (P ＜ 0.05).Conclusion The serum thyroid hormone levels decrease obviously in elderly congestive heart failure patients with depression and low T3 syndrome occurrs easily,so this should arouse more attention in clinic.It is necessary to do regular thyroid function tests.