Effect of insulin on the expression of human urate transporter gene in renal proximal tubule epithelial HK-2 cells / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 282-284, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-470524
ABSTRACT
Human proximal tubule epithelial cell line,HK-2 cells,were cultured with various concentrations of insulin for 48 h.Human urate transporter (hUAT) mRNA was detected by realtime quantitative PCR.hUAT mRNA levels were down-regulated by insulin (5,25,125,500 μIU/ml)in a dose-dependent manner (relative expression median were 0.95,0.40,0.24,and 0.23).In vitro,the expression of hUAT mRNA in HK-2 cells is associated with the concentration of insulin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2015
Type:
Article
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