Research progress of patient-derived xenograft model / 国际外科学杂志
International Journal of Surgery
;
(12): 50-52, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-470958
ABSTRACT
Tumor cell line culture technologies emerged as a strong impetus to the development of tumor biology research.However,cell line tumor model presented limited predictive value and instable properties in the clinical translational research of new cancer therapies.Recently Patient-derived Xenograft Model (PDX) has aroused researcher's attention and been widely applied to new cancer therapy research.This new model could highly retain the stroma heterogeneity、histological characteristics and molecular diversity of the original tumor,and is expected to bring new breakthroughs in individualized treatment of tumor patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2015
Type:
Article
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