Treatment of refractory and relapsed acute leukemia in 25 adult patients with MAAE regimen / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 129-130, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-471981
ABSTRACT
Objective To analyze on the efficacy and toxicity of MAAE (MIT ,Ara-C,AMSA,VP16)regimens on treating refractory and relapsed acute leukemia in adult patients. Methods MAAE (MIT, Ara-C,AMSA, VP16) regimen, which consisted of MIT 10mg/d (d1~3), intravenousdrop, Ara-C 200mg/d (d1~7),intravenousdrop, AMSA 75 mg/d (d1~3), intravenousdrop VP16 100 mg/d(d1~4), intravenousdrop were used to treat 25 cases of adults with refractory and relapsed acute leukemia (AL). G-CSF 5 μg/kg were used every day when WBC<0.5×109/L. Results In the 25 cases with refractory and relapsed acute leukemia, 14 cases (56 %) reached complete remission, 5 patients(20 %) reached partial remission, the total effective rate was 76 %. Conclusion MAAE regimen was a very effective alternative treatment for CR induction in adult patients with refractory and relapsed AL and low toxicity.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2008
Type:
Article
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