A Clinical Study of Faropenem on Treatment of Acute Bacterial Infections / 天津医药
Tianjin Medical Journal
;
(12): 849-852, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-472608
ABSTRACT
Objective:
To evaluate the clinical efficacy and safety of domestic faropenem in the treatment of acute bacterial infections.Methods:
A multicenter, randomized, double blind and double simulation clinical study was conducted to compare the efficacy and safety of faropenem and cefaclor in the treatment of acute bacterial infection. Patients in trial group(n = 122) were given faropenem 250 mg,and in control group (n = 118) were given cefaclor 200 mg,3 times daily for 7 to 10 days.Results:
The clinical cure rates were 33.61% and 27.12% in trail and control groups respectively and the clinical effective rates were 87.70% and 83.05% respectively. There was no significant difference in terms of clinical effectiveness between the two groups(P > 0.05). The adverse reaction rates were 7.32% in trial group and 3.36% in control group(P > 0.05). The adverse reaction of the trial group was mainly exaltation of aminotransferase, which did not affect the therapy. No severe adverse reaction was found.Conclusion:
Domestic faropenem is effective and safe for the treatment of bacterial respiratory tract and urinary tract infections.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Tianjin Medical Journal
Year:
2009
Type:
Article
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