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Clinical Study on Acupuncture in Treating Diarrhea-predominant Irritable Bowel Syndrome / 针灸推拿医学(英文版)
Journal of Acupuncture and Tuina Science ; (6): 360-362, 2008.
Article in Chinese | WPRIM | ID: wpr-472809
ABSTRACT

Objective:

To observe the changes of 5-hydroxytryptamine (5-HT) in colonic membrane of diarrhea-predominant irritable bowel syndrome (IBS-D) and the clinical efficacy of herbal cake-partitioned moxibustion in treating it, and to explore the action mechanisms.

Methods:

Seventy-three subjects were randomized into two groups moxibustion group in which 37 cases were treated by herbal cake-partitioned moxibustion and needling group in which 36 cases were treated by needling. The clinical efficacy and 5-HT expression in colonic membrane were observed.

Results:

The cure rate was 43.2% in the moxibustion group and 36.1% in the needling group, with no significant difference between the two groups (P>0.05). Herbal cake-partitioned moxibustion could reduce 5-HT expression in colonic membrane.

Conclusion:

Herbal cake-partitioned moxibustion might improve the clinical symptoms of IBS-D by reducing 5-HT expression.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Acupuncture and Tuina Science Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Acupuncture and Tuina Science Year: 2008 Type: Article