Research progress of phosphatase of regenerating liver-3 in tumors / 肿瘤研究与临床

ABSTRACT

Phosphatase of regenerating liver-3 (PRL-3) is one of member in the protein tyrosine phosphatase (PTP) family.Since high expression of PRL-3 was first discovered in liver metastasis patients with colon cancer,many researchers found that PRL-3 also high expressed in multiple organs like cancer from breast,prostate,liver,stomach,lung,kidney and so on.This paper focused on correlation of PRL-3 with the occurrence and metastasis of tumors.