Research progress of the relevance between tumor and human leukocyte antigen / 肿瘤研究与临床

ABSTRACT

Human leukocyte antigen (HLA) has high polymorphism at the genetic level,which is one of the important molecules in human immune response,lack-or over-expression will lead to abnormal immune response.The escape ot tumor from the immune damage is a possible mechanism of tumor occurrence and development.Further study about the relationship between abnormal expression of HLA and the tumor may provide important evidence on the study of mechanism of tumorigenesis and tumor immunotherapy.