The Relationship between Different Iodine Intake and Thyroid Function in Adults / 天津医药
Tianjin Medical Journal
;
(12): 164-166, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-473214
ABSTRACT
Objective:
To observe the effect of different iodine intake on the thyroid function in euthyroid adult persons.Methods:
One hundred and sixty-one euthyroid healthy volunteers aged 18-24 years were randomly divided into 7 groups.Each group was assigned to receive 500 μg,750 μg,1 000 μg,1 250 μg,1 500 μg,and 2 000 μg iodide/day for four weeks.Serum concentrations of free triiodothyronine(FT3),free thyroxin(FT4)and sensitive thyroid-stimulating hormone(sTSH)were measured by chemolumineseenee assays.Results:
Serum FT3 concentration was found a small decline within the normal range in all the iodide supplemented groups(P < 0.05).The level of FT4 was significantly lower,when the dose was up to 1 500 μg (P < 0.05).The level of serum sTSH was increased after 2 weeks iodide supplement in all groups,and after 4 weeks in 500 μg and 750 μg groups(P < 0.05).No significant changes were observed in FT3,FT4 and sTSH between groups(P> 0.05).Conclusion:
The thyroid function of normal people showed a rise in serum sTSH at a short time and a high-dose of iodine intake.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Tianjin Medical Journal
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS