Moxibustion on Telomerase Activity in Aging Rat / 针灸推拿医学(英文版)
Journal of Acupuncture and Tuina Science
;
(6): 74-78, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-473431
ABSTRACT
Objective:
To investigate the effect of moxibustion on telomerase activity and genes expression in tissues of senescent rats.Methods:
Subacute aging rats model were established by injection with D-gal solution. Points Shenshu (BL 23) were treated with moxibustion in treatment group, contrasting with a model group and a normal group. Enzyme-Linked Immunosorbent Assays(ELISA) was used for the level oftelomerase activity in liver tissues, and In Situ Hybridization(ISH) was used for the condition of expression of telomerase genes in liver tissues.Results:
The level of telomerase activity in the aging model group was obviously lower than that in normal control group (P<0.01), the level in moxibustion group was obviously higher than that in model group(P<0.05). In comparison with normal rats, the positive-expressed areas and photodensity of telomerase genes in aging model group were all significantly lower (P<0.01,P<0.01), and the positive-expressed areas in moxibustion group was significantly higher than that in model group (P<0.01).Conclusions:
Moxibustion could regulate telomerase activity of senile rats, hence delaying aging.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Acupuncture and Tuina Science
Year:
2007
Type:
Article
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