Value of Continuous Renal Replacement Therapy in the Treatment of the Type 1 Cardiorenal Syndrome / 医学研究杂志

ABSTRACT

Objective To evaluate the value of Continuous renal replacement therapy ( CRRT) in the treatment of the type 1 cardio-renal syndrome.Methods From June 2008 to August 2014,the type 1 cardiorenal syndrome patients receiving continuous renal replace-ment therapy in Wenzhou People′s Hospital ICU were retrospectively analyzed .Before and after treatment , the mean arterial pressure , central venous pressure, shock index, rapid shallow breathing index, oxygenation index, urine, plasma amino-terminal pro-B-type natriuretic peptide precursor , creatinine and bicarbonate and other clinical data were observed in order to understand CRRT ′s value in type 1 cardiorenal syndrome patients.Results Total 37 patients [aged from 27-88(67.9 ±18.7)years,51.4%male] with type 1 cardiore-nal syndrome were enrolled in this study .Statistics showed that after CRRT treatment , the mean arterial pressure , central venous pres-sure, shock index , rapid shallow breathing index , oxygenation index , urine, plasma amino-terminal pro-B-type natriuretic peptide precursor, creatinine and bicarbonate were significantly improved , and there was a significant difference (P<0.05).Conclusion For type 1 cardiorenal syndrome , especially critical patients with serious diuretic resistance , CRRT has great therapeutic value , even the only treatment option .