Analysis of clinical characteristics and etiology of inpatients with neonatal hyperbilirubinemia in Chenzhou area / 国际检验医学杂志

ABSTRACT

Objective To analyse clinical characteristics and etiology of inpatients with neonatal hyperbilirubinemia in Chenzhou area.Methods A total of 534 cases of inpatients with neonatal hyperbilirubinemia in Children′s Hospital,First People′s Hospital of Chenzhou City were selected from January to December 2012 and their clinical data were collected.The levels of total bilirubin,hu-man cytomegalovirus (HCMV)gene,and enzymatic activity of glucose-6-phos-phate dehydrogenase (G-6PD)were detected.And screening of hemolytic disease of newborn was carried out as well.Data were statistically analysed.Results Among these patients with neonatal hyperbilirubinemia,43 cases of neonatal patients were diagnosed with G-6PD deficiency(accounted for 8.0%),98 ca-ses of neonatal patients were diagnosed with ABO hemolytic disease(accounted for 18.4%),1 53 cases of neonatal patients were di-agnosed with HCMV infection(accounted for 28.6%)and 149 cases of neonatal patients were diagnosed with bacterial infections (accounted for 27.9%).Conclusion The main etiology of patients with neonatal hyperbilirubinemia in this area is infectious factor. Strengthening monitoring bilirubin in neonatal patients,and analysing test results and etiology could effectively reduce damages in-duced by neonatal hyperbilirubinemia.