Bioinformatics prediction on glutathione S-transferase antigen epitopes of Echinoccocus granulosus / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 1818-1820, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-473958
ABSTRACT
Objective To analyse the secondary structure of glutathions S-transferase of Echinoccocus granulosus(EgGST)and predict the B cell and T cell epitopes with informatics tools,in order to provide basic data and references for the following design of epitope vaccine.Methods The B cell and T cell epitopes of EgGST were predicted by DNAstar,Biosun software and Propred MHC class-Ⅱ Binding Peptide Prediction Server software.Results Many distinct antigenic epitopes of EgGST were identified by comput-er,there existed 8 B cell epitopes and 7 T cell epitopes.Conclusion Analysis of predicted epitopes of EgGST antigenic might be sig-nificant for future research of epitope vaccine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
International Journal of Laboratory Medicine
Year:
2015
Type:
Article
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