Analysis of different diagnostic methods for differentiating biliary atresia from hepatitis syndrome / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 652-655, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-474648
ABSTRACT
Objective To retrospectively evaluate different methods (laboratory tests,liver / gallbladder ultrasound and magnetic resonance cholangiopancreatography)in differentiating biliary atresia from infant hepatitis syndrome.Methods Seventy infants with cholestatic jaundice,50 cases of biliary atresia and 20 cases of infant hepatitis syndrome were studied prospectively from January 2010 to December 2012.All cases underwent abdominal ultrasound and magnetic resonance cholangiopancreatography.The accuracy,sensitivity,specificity and predictive values of these various methods were compared.Also the laboratory parameters were statistically analyzed and compared between groups.Results Patients with BA had significantly higher GGT values at presentation [(743.5 ± 564) IU/L] compared with infants with IHS [(198.8 ± 197.8) IU/L],showing statistically significant difference (P < 0.05).The sensitivity,specificity,and accuracy of the ultrasound in diagnosis of BA were 84.0% 、100.0% 、88.6% respectively(P < 0.05).The values for magnetic resonance cholangiopancreatography were 82.0% 、80.0% 、81.4% (P < 0.05).Conclusion Currently,the method of ultrasound is more reliable than MRCP for differentiating biliary atresia from infant hepatitis syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2014
Type:
Article
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