Circadian rhythm changes of PGE2 levels in blood of growing rats after functional mandibular protrusion / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 757-759, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-475182
ABSTRACT
Objective:
To explore the relationship between wearing of functional appliance and systemic metabolism of PGE2 in the blood of growing rats.Methods:
54 male Wistar rats aged 4-weeks were randomly divided into 3 groups(n =18)Daytime group,all-day group and control group.Self-guided functional appliance was made for mandible advancement of the rats in the 2 experimental groups.One week after appliance wearing,rats were sacrificed at the corresponding time points and blood in femoral artery was taken. PGE2 levels in the blood samples were measured,data were analysed by cosine equation.Results:
Hypothesis was true in the control group(P <0.05),and was not true in both 2 experimental groups(P >0.05).Conclusion:
PGE2 level in rat blood is circadian rhyth-mic,wearing of functional appliance made may disturb the rhythm.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2014
Type:
Article
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