Progress of E.coli producing extended spectrum beta-lactameses in children with urinary tract infection / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 14-17, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-475391
ABSTRACT
Urinary tract infections (UTI)is a childhood disease.With the use of extended spectrum antibiotics,resistant strains have increased every year,especially Escherichia coli(E.coli).The mechanisms of drug resistance are as followshydrolase,target gene mutations,efflux pumps and membrane permeability change.Of which producing extended-spectrum β-lactamase(ESBL) is increasing.So it presents a huge challenge to clinical antibiotic selection.According to the resistance genes (blaTEM,blaSHV,blaCTX-M,etc.),the ESBL can be classified into different types (TEM type,SHV-type,CTX-M type,etc.).The drug-resistant genes play an important role in spreading and prevalence of the resistance genes.It's necessary to do a review of the currently known genotypes.It is both in favor of scientific research work and providing guidance for clinical work.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2015
Type:
Article
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