A Case of Peripheral T-cell Lymphoma Manifesting Bilateral Periobital Infiltration with Swelling / 대한피부과학회지

ABSTRACT

Periorbital swelling is a rather common symptom. Of the causes, the associated lymphoproliferative diseases rarely involve, and, if any, pseudolymphoma and B-cell type of lymphoma are mostly implicated. We report herein a case of unspecified peripheral T-cell lymphoma presenting as only manifestation of bilateral orbital swelling. A 32-year-old woman had a fluctuant course of bilateral mild erythematous swelling without ocular or lymph node involvement for about 2 years. Biopsy specimens from the left upper eyelid showed infiltration of medium-sized atypical cells with pleomorphism, convoluted nuclei, scant cytoplasm and less prominent nuclei. The cell was LCA, UCHL-1 and CD3 positive, but negative for L26. She received six cycles of CHOP combined therapy, with a marked improvement. No relapse was noted during a period of about a 6-month follow-up.