Progress in diagnosis and treatment of pseudomembranous colitis / 国际儿科学杂志

ABSTRACT

Pseudomembranous colitis occurred is closely related to the use of antibiotics and the pathogenic bacteria approximately 100％ is clostridium difficile.Diagnosis is mainly based on clinical manifestations,stool culture,toxin detection,colonoscopy and/or histological examination.Once the diagnosis has been confirmed or highly suspected,the initial antibiotic therapy should be discontinued,add with metronidazole and/or vancomycin,supplement by probiotic and nutritional support.The recent years,new treatment options have been proposed.This article presents an review of the related situation of pseudomembranous colitis to improve the comprehension for clinical doctors.