Influence of Bailing Capsules Combined with Breviscapine Injections on Micro-inflamation in Patients with Peritoneal Dialysis / 中国药师

ABSTRACT

Objective:To explore the effects of Bailing capsules combined with breviscapine injections on the micro-inflammation in the patients with peritoneal dialysis. Methods:Sixty-five patients with peritoneal dialysis for more than 6 months were randomly di-vided into the treatment group (33 patients) and the control group (32 patients). The two groups were still given peritoneal dialysis and treated with the conventional symptomatic treatment combined with breviscapine, while in the treatment group, Bailing capsules were given additionally. Before and after the 2-week treatment, serum creatinine, urea, plasma albumin, hs-CRP and IL-6 were exam-ined and compared in the two groups. Results:After the treatment, serum creatinine and urea in the two groups were significantly de-creased(P<0. 05), and plasma albumin was increased significantly(P<0. 05), and the changes in the treatment group were more no-table than those in the control group (P<0. 05). After the treatment, the average levels of hs-CRP and IL-6 were decreased signifi-cantly in the two groups (P<0. 05 or P<0. 01), and those in the treatment group were lower than those in the control group (P<0. 01). Conclusion:The combined therapy of Bailing capsules and breviscapine injections shows better clinical effects on the micro-inflammation in the patients with peritoneal dialysis than breviscapine injections alone.